HBZ

Across TCGA patient cohorts, HBZ protein abundance is significantly associated with the protein abundance of many other proteins, with 19,628 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HBZ-associated proteins across cancer lineages are ANK1, SPTA1, and HBD. Each is linked with HBZ in more than 9 cancer types. Because this analysis shows association rather than direction, both HBZ-to-partner and partner-to-HBZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HBZ versus ANK1 in CCRCC, with a Pearson correlation of 0.92.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HBZ→partner) and Y-score (partner→HBZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ANK1 →	+1.515	+1.469	<.001	<.001	3	10
CCRCC	SPTA1 →	+1.728	+1.471	<.001	<.001	3	9
CCRCC	HBD →	+1.654	+1.505	<.001	<.001	3	9
CCRCC	BPGM →	+1.159	+1.462	<.001	<.001	3	9
CCRCC	AHSP →	+1.489	+1.328	<.001	<.001	3	9
CCRCC	EPB42 →	+1.540	+1.467	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,628 associations by consensus.

HBZ vs ANK1 — CCRCC

Explore this scatter interactively →