HAUS4

Across TCGA pan-cancer cohorts, HAUS4 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated HAUS4 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher HAUS4 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated HAUS4 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and PDAC are the cancer types where HAUS4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	1.000	0.900	.007	28	view →
LSCC	OS	Tertile	II,III,IV	0.941	0.541	.003	19	view →
PDAC	OS	Tertile	All	0.233	0.620	.008	8	view →
HNSC	OS	Tertile	IV	0.871	0.476	.010	6	view →
CCRCC	DFS	Median	II,III,IV	0.507	0.788	.016	5	view →
OV	DFS	Tertile	All	0.797	1.000	.035	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

HAUS4–LUAD (OS)

Open the LUAD breakdown →