HAUS4

Across TCGA patient cohorts, HAUS4 mutation is significantly associated with the RNA expression of many other genes, with 767 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HAUS4-associated genes across cancer lineages are NTAN1, SLC27A4, and DDX19A. Each is linked with HAUS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAUS4-to-partner and partner-to-HAUS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NTAN1 grouped by HAUS4-low versus HAUS4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS4→partner) and Y-score (partner→HAUS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NTAN1 →	+0.490	+2.276	.001	.005	3	2
UCEC	SLC27A4 →	+0.487	+2.546	.004	.009	3	2
UCEC	DDX19A →	+0.453	+2.243	.003	.006	3	2
UCEC	CTU2 →	+0.401	+2.233	.006	.006	3	2
UCEC	RAD51 →	+0.689	+2.233	.003	.006	3	2
UCEC	IFRD1 →	+0.690	+4.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 767 associations by consensus.

NTAN1 by HAUS4 expression — UCEC

Explore this box plot interactively →