HAUS4

Across TCGA cell cohorts, HAUS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,857 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HAUS4-associated GO terms across cancer lineages are DNA synthesis involved in DNA replication, Pericentric heterochromatin formation, and DNA ADP-ribosylation. Each is linked with HAUS4 in more than 9 cancer types. Because this analysis shows association rather than direction, both HAUS4-to-partner and partner-to-HAUS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA synthesis involved in DNA replication grouped by HAUS4-low versus HAUS4-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS4→partner) and Y-score (partner→HAUS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DNA synthesis involved in DNA replication →	+0.069	+0.530	<.001	<.001	3	10
OVARY	Pericentric heterochromatin formation →	+0.154	+0.652	<.001	<.001	3	10
KIDNEY	DNA ADP-ribosylation →	+0.127	+0.690	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Translesion synthesis →	+0.065	+1.003	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	DNA damage tolerance →	+0.085	+0.965	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.091	+1.207	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,857 associations by consensus.

DNA synthesis involved in DNA replication by HAUS4 expression — CNS

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