HAT1

Across TCGA patient cohorts, HAT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,799 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HAT1-associated proteins across cancer lineages are RRM2, MCM4, and MCM5. Each is linked with HAT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HAT1-to-partner and partner-to-HAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAT1 versus RRM2 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAT1→partner) and Y-score (partner→HAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.885	+0.443	<.001	<.001	3	8
LUAD	MCM4 →	+0.672	+0.321	<.001	<.001	3	8
LUAD	MCM5 →	+0.641	+0.321	<.001	<.001	3	8
UCEC	MCM6 →	+0.748	+0.432	<.001	<.001	3	8
UCEC	MCM7 →	+0.660	+0.386	<.001	<.001	3	8
OV	C9orf78 →	+0.291	+0.432	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,799 associations by consensus.

HAT1 vs RRM2 — UCEC

Explore this scatter interactively →