HAPLN3

Across TCGA cell cohorts, HAPLN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,369 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HAPLN3-associated GO terms across cancer lineages are Protein folding, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with HAPLN3 in more than 14 cancer types. Because this analysis shows association rather than direction, both HAPLN3-to-partner and partner-to-HAPLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by HAPLN3-low versus HAPLN3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN3→partner) and Y-score (partner→HAPLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein folding →	+0.054	+0.972	.001	.001	2	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.097	+0.834	<.001	<.001	3	13
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.110	+2.086	<.001	<.001	3	13
LIVER	Protein stabilization →	+0.044	+2.138	<.001	.005	3	11
BONE	Regulation of stem cell proliferation →	+0.167	+2.435	.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.082	+1.092	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,369 associations by consensus.

Protein folding by HAPLN3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →