HAO2-IT1

Across TCGA patient cohorts, HAO2-IT1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,719 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HAO2-IT1-associated genes across cancer lineages are HSD3BP1, HAO2, and HSD3BP2. Each is linked with HAO2-IT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both HAO2-IT1-to-partner and partner-to-HAO2-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAO2-IT1 versus HSD3BP1 in ACC, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAO2-IT1→partner) and Y-score (partner→HAO2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	HSD3BP1 →	+1.171	+0.479	<.001	<.001	3	14
LIHC	HAO2 →	+3.380	+0.908	<.001	<.001	3	13
PCPG	HSD3BP2 →	+3.146	+0.135	<.001	<.001	3	12
MESO	GAPDHP74 →	+1.398	+0.407	<.001	<.001	3	11
PCPG	HSD3B2 →	+7.440	+0.229	<.001	<.001	3	10
PCPG	GSTA7P →	+1.586	+0.415	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,719 associations by consensus.

HAO2-IT1 vs HSD3BP1 — ACC

Explore this scatter interactively →