HAO2-IT1

Across TCGA patient cohorts, HAO2-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,129 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HAO2-IT1-associated proteins across cancer lineages are SORBS2, IRAK1, and TIMM50. Each is linked with HAO2-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HAO2-IT1-to-partner and partner-to-HAO2-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAO2-IT1 versus SORBS2 in CCRCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAO2-IT1→partner) and Y-score (partner→HAO2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SORBS2 →	+0.397	+0.783	.002	.001	3	3
PDAC	IRAK1 →	-0.278	-0.548	.001	<.001	3	3
LSCC	TIMM50 →	-0.348	-0.152	.004	.004	3	2
LSCC	NCAM1 →	+0.549	+0.167	.004	.003	2	3
LUAD	REG3A →	+2.718	+0.590	.001	.003	3	2
LUAD	RSRC1_S48 →	+0.343	+0.112	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,129 associations by consensus.

HAO2-IT1 vs SORBS2 — CCRCC

Explore this scatter interactively →