HAGHL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HAGHL protein abundance is significantly associated with the RNA expression of many other genes, with 7,009 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HAGHL-associated genes across cancer lineages are ELF4, CA9, and UGT8. Each is linked with HAGHL in more than 1 cancer types. Because this analysis shows association rather than direction, both HAGHL-to-partner and partner-to-HAGHL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAGHL versus ELF4 in LUAD, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAGHL→partner) and Y-score (partner→HAGHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADELF4 →-0.855-0.397.007.00232
LUADCA9 →-2.309-0.397.001.00232
LUADUGT8 →-1.646-0.397.001.00132
BRCAPRLH →+0.398+0.396.009<.00132
BRCADICER1 →+0.742+0.574.002.00132
BRCAEEF1A2 →+1.696+0.398<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,009 associations by consensus.

HAGHL vs ELF4 — LUAD

Per-sample scatter of HAGHL vs ELF4 in LUAD (Pearson r = -0.48).

Explore this scatter interactively →

Exploration