H4C6

Across TCGA patient cohorts, H4C6 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,849 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H4C6-associated proteins across cancer lineages are PYHIN1, BIN2, and DEF6_S590. Each is linked with H4C6 in more than 2 cancer types. Because this analysis shows association rather than direction, both H4C6-to-partner and partner-to-H4C6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H4C6 versus PYHIN1 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C6→partner) and Y-score (partner→H4C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PYHIN1 →	+0.650	+1.378	<.001	.002	3	3
PDAC	BIN2 →	+0.318	+0.704	<.001	<.001	3	3
CCRCC	DEF6_S590 →	+0.455	+0.619	<.001	.001	3	3
LSCC	FMNL1_S1031 →	+0.632	+1.324	<.001	<.001	3	3
PDAC	ITGAL →	+0.348	+0.577	<.001	<.001	3	3
HNSC	WDR12_T221 →	-0.492	-2.331	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,849 associations by consensus.

H4C6 vs PYHIN1 — UCEC

Explore this scatter interactively →