H4C13

Across TCGA patient cohorts, H4C13 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible H4C13-associated genes across cancer lineages are RNU6-173P, HERC2P11, and NOS2P1. Each is linked with H4C13 in more than 1 cancer types. Because this analysis shows association rather than direction, both H4C13-to-partner and partner-to-H4C13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-173P grouped by H4C13-low versus H4C13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C13→partner) and Y-score (partner→H4C13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-173P →	+0.595	+4.937	<.001	.005	3	2
BLCA	HERC2P11 →	+0.106	+4.973	<.001	.009	3	1
BLCA	NOS2P1 →	+0.024	+5.177	<.001	.007	3	1
BRCA	RNU6-922P →	+0.364	+5.646	<.001	.004	3	1
BRCA	MIR3937 →	+0.208	+7.471	<.001	.008	3	1
BRCA	OR5AL1 →	+0.092	+7.471	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

RNU6-173P by H4C13 expression — UCEC

Explore this box plot interactively →