H3P35

Across TCGA patient cohorts, H3P35 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,481 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible H3P35-associated proteins across cancer lineages are RGN, PXN_S303, and PLCL1. Each is linked with H3P35 in more than 3 cancer types. Because this analysis shows association rather than direction, both H3P35-to-partner and partner-to-H3P35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3P35 versus RGN in PDAC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P35→partner) and Y-score (partner→H3P35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RGN →	+0.747	+0.597	<.001	.001	3	4
UCEC	PXN_S303 →	+0.323	+0.539	.001	.004	3	3
GBM	PLCL1 →	+0.442	+0.334	.001	.001	2	4
LUAD	RPS3_T221 →	-0.440	-0.235	<.001	.001	3	3
PDAC	SNRK →	+0.253	+0.526	<.001	.001	3	3
PDAC	TEP1_S397 →	-0.424	-0.633	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,481 associations by consensus.

H3P35 vs RGN — PDAC

Explore this scatter interactively →