H3P18

Across TCGA patient cohorts, H3P18 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,404 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P18-associated GO terms across cancer lineages are Inner mitochondrial membrane organization, Intrinsic apoptotic signaling pathway in response to oxidative stress, and Negative regulation of nervous system development. Each is linked with H3P18 in more than 7 cancer types. Because this analysis shows association rather than direction, both H3P18-to-partner and partner-to-H3P18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Inner mitochondrial membrane organization grouped by H3P18-low versus H3P18-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P18→partner) and Y-score (partner→H3P18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Inner mitochondrial membrane organization →	+0.132	+0.067	<.001	<.001	3	8
STAD	Intrinsic apoptotic signaling pathway in response to oxidative stress →	+0.117	+0.050	<.001	<.001	3	8
STAD	Negative regulation of nervous system development →	+0.077	+0.063	<.001	<.001	3	8
STAD	Cytoskeleton-dependent intracellular transport →	+0.110	+0.063	<.001	<.001	3	8
STAD	Mitral valve development →	+0.099	+0.083	<.001	<.001	3	8
STAD	Placenta development →	+0.125	+0.067	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,404 associations by consensus.

Inner mitochondrial membrane organization by H3P18 expression — STAD

Explore this box plot interactively →