Q-omics provides the consensus-scored H3P18 profile across patient tissues and cancer cell-line models. H3P18 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, H3P18 RNA expression shows 8,075 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight BLCA, and TGCT as cancer lineages where H3P18 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes H3P18 survival associations across molecular data types. H3P18 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

H3P18 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	BLCA (114)	view →

This table ranks reproducible H3P18 RNA expression–survival associations across cancer types. High H3P18 expression shows unfavorable associations in BLCA, UVM, CESC, HNSC and BRCA, but favorable associations in LUAD. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for H3P18 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.306	0.666	<.001	114	view →
UVM	OS	Tertile	II,III,IV	0.303	0.735	<.001	84	view →
CESC	OS	Tertile	IV	0.091	0.593	<.001	54	view →
LUAD	DFS	Tertile	All	0.938	0.630	.015	48	view →
HNSC	OS	Tertile	II,III,IV	0.540	0.726	.019	42	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →

Pink = unfavorable, green = favorable. all 13 lineages →

H3P18-BLCA (OS)

Kaplan–Meier survival curve for H3P18 RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with H3P18 in patient tissues and cancer cell lines. In patient samples, H3P18 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,075	TGCT (3610)	view →
Function (RNA)	6,404	STAD (5509)	view →