H3-3B

Across TCGA patient cohorts, H3-3B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,889 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H3-3B-associated proteins across cancer lineages are UBE2O, HEATR6, and PRPSAP1. Each is linked with H3-3B in more than 5 cancer types. Because this analysis shows association rather than direction, both H3-3B-to-partner and partner-to-H3-3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3-3B versus UBE2O in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3-3B→partner) and Y-score (partner→H3-3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBE2O →	+0.298	+0.707	<.001	<.001	3	6
BRCA	HEATR6 →	+0.404	+0.624	.009	<.001	3	6
OV	PRPSAP1 →	+0.229	+0.442	.001	.001	3	5
HNSC	IRF4 →	-0.911	-0.498	<.001	<.001	3	5
GBM	JPT1 →	+0.374	+0.283	.008	<.001	3	5
PDAC	BAIAP2 →	+0.587	+0.471	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,889 associations by consensus.

H3-3B vs UBE2O — BRCA

Explore this scatter interactively →