H2BW3P

Across TCGA patient cohorts, H2BW3P mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2BW3P-associated genes across cancer lineages are RNU4-58P, RNU6-280P, and RNA5SP72. Each is linked with H2BW3P in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BW3P-to-partner and partner-to-H2BW3P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by H2BW3P-low versus H2BW3P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BW3P→partner) and Y-score (partner→H2BW3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-58P →	+0.681	+5.133	<.001	.008	3	1
UCEC	RNU6-280P →	+0.737	+7.245	<.001	<.001	3	1
UCEC	RNA5SP72 →	+0.770	+5.031	<.001	.009	3	1
UCEC	RNU6-1141P →	+0.662	+5.081	.005	.008	3	1
UCEC	SNORD114-18 →	+1.053	+5.299	<.001	.006	3	1
UCEC	MIR629 →	+0.867	+6.582	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RNU4-58P by H2BW3P expression — UCEC

Explore this box plot interactively →