H2BW2

Across TCGA patient cohorts, H2BW2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,347 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2BW2-associated genes across cancer lineages are ADGRG3, PTPN22, and CSF3R. Each is linked with H2BW2 in more than 5 cancer types. Because this analysis shows association rather than direction, both H2BW2-to-partner and partner-to-H2BW2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2BW2 versus ADGRG3 in PDAC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BW2→partner) and Y-score (partner→H2BW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ADGRG3 →	+1.131	+0.672	<.001	<.001	3	6
OV	PTPN22 →	+0.840	+0.714	.001	.002	3	5
GBM	CSF3R →	+0.966	+0.553	.001	<.001	3	5
HNSC	ARHGAP9 →	+0.968	+0.351	<.001	<.001	3	5
HNSC	ITGAX →	+0.901	+0.451	<.001	<.001	3	5
LSCC	CXCR1 →	+1.092	+0.473	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,347 associations by consensus.

H2BW2 vs ADGRG3 — PDAC

Explore this scatter interactively →