H2BC9

Across TCGA cell cohorts, H2BC9 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible H2BC9-associated genes across cancer lineages are MYH8, OR10K2, and OR10T2. Each is linked with H2BC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC9-to-partner and partner-to-H2BC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH8 grouped by H2BC9-low versus H2BC9-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC9→partner) and Y-score (partner→H2BC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MYH8 →	+0.022	+4.781	<.001	.003	3	1
BREAST	OR10K2 →	+0.047	+4.781	<.001	.003	3	1
BREAST	OR10T2 →	+0.137	+4.781	<.001	.003	3	1
BREAST	FAM47B →	+0.012	+4.781	<.001	.003	3	1
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MYH8 by H2BC9 expression — BREAST

Explore this box plot interactively →