Across TCGA patient cohorts, H2BC21 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,844 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2BC21-associated proteins across cancer lineages are RFC1_S368, RRM2_S20, and ATAD2_S342. Each is linked with H2BC21 in more than 6 cancer types. Because this analysis shows association rather than direction, both H2BC21-to-partner and partner-to-H2BC21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC21→partner) and Y-score (partner→H2BC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RFC1_S368 →	+0.824	+0.739	<.001	<.001	3	7
LUAD	RRM2_S20 →	+1.153	+0.722	<.001	<.001	3	7
GBM	ATAD2_S342 →	+1.150	+0.913	<.001	<.001	3	7
GBM	SUPT16H →	+0.386	+0.693	<.001	<.001	3	7
LUAD	CDK1 →	+0.825	+0.747	<.001	<.001	3	7
LUAD	HMGB3 →	+0.873	+0.622	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,844 associations by consensus.

Exploration

H2BC21 survival (RNA) · tumor vs normal (RNA) · all H2BC21 data types