H2AZ1-DT

Across TCGA patient cohorts, H2AZ1-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 9,873 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2AZ1-DT-associated proteins across cancer lineages are DNAJC1, MEPCE, and CBX8. Each is linked with H2AZ1-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both H2AZ1-DT-to-partner and partner-to-H2AZ1-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AZ1-DT versus DNAJC1 in PDAC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AZ1-DT→partner) and Y-score (partner→H2AZ1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DNAJC1 →	-0.358	-0.105	<.001	.001	3	5
GBM	MEPCE →	+0.321	+0.298	<.001	.005	3	4
OV	CBX8 →	+0.446	+0.403	<.001	.001	3	4
CCRCC	VEZF1 →	+0.330	+0.252	.001	.001	3	4
LSCC	ISG20 →	-0.480	-0.208	<.001	<.001	3	4
OV	RIPK3 →	-0.419	-0.365	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,873 associations by consensus.

H2AZ1-DT vs DNAJC1 — PDAC

Explore this scatter interactively →