Across TCGA patient cohorts, H2AP RNA expression is significantly associated with the protein abundance of many other proteins, with 7,035 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2AP-associated proteins across cancer lineages are SYTL5_S169, FAM114A2, and DYNLT3. Each is linked with H2AP in more than 3 cancer types. Because this analysis shows association rather than direction, both H2AP-to-partner and partner-to-H2AP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AP→partner) and Y-score (partner→H2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYTL5_S169 →	+1.864	+0.920	<.001	.001	3	4
LUAD	FAM114A2 →	-0.185	-0.214	<.001	<.001	3	4
BRCA	DYNLT3 →	+0.323	+0.452	<.001	<.001	3	4
BRCA	TAPBP →	-0.360	-0.313	.004	<.001	3	3
LSCC	PLEKHA1 →	+0.458	+0.567	<.001	<.001	3	3
BRCA	CFLAR →	-0.238	-0.290	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,035 associations by consensus.

Exploration

H2AP survival (RNA) · tumor vs normal (RNA) · all H2AP data types