Across TCGA cell cohorts, H2AP RNA expression is significantly associated with the go_rna of many other GO terms, with 371 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible H2AP-associated GO terms across cancer lineages are Pyramidal neuron development, Response to fluid shear stress, and Response to topologically incorrect protein. Each is linked with H2AP in more than 2 cancer types. Because this analysis shows association rather than direction, both H2AP-to-partner and partner-to-H2AP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AP→partner) and Y-score (partner→H2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Pyramidal neuron development →	+0.103	+0.052	.001	.001	3	3
LUNG_NSCLC_LUAD	Response to fluid shear stress →	+0.053	+0.043	.003	.009	3	3
LUNG_NSCLC_LUAD	Response to topologically incorrect protein →	+0.054	+0.080	.003	.009	3	3
LUNG_NSCLC_LUAD	Intestinal lipid absorption →	-0.155	-0.043	.007	.008	3	3
LARGE_INTESTINE	Negative regulation of heart rate →	-0.183	-0.125	.001	.008	3	3
BREAST	Regulation of response to macrophage colony-stimulating factor →	-0.601	-0.105	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

Exploration

H2AP survival (RNA) · tumor vs normal (RNA) · all H2AP data types