H2AL1QP

Across TCGA patient cohorts, H2AL1QP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,095 significant associations in total. LGG shows the largest number of these associations.

The most reproducible H2AL1QP-associated GO terms across cancer lineages are Intracellular glucose homeostasis, Mitochondrial membrane organization, and Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Each is linked with H2AL1QP in more than 6 cancer types. Because this analysis shows association rather than direction, both H2AL1QP-to-partner and partner-to-H2AL1QP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular glucose homeostasis grouped by H2AL1QP-low versus H2AL1QP-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AL1QP→partner) and Y-score (partner→H2AL1QP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intracellular glucose homeostasis →	+0.052	+0.031	<.001	.004	2	7
STAD	Mitochondrial membrane organization →	+0.079	+0.048	<.001	<.001	3	5
STAD	Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway →	+0.070	+0.035	<.001	.001	3	5
KICH	CDP-choline pathway →	+0.051	+0.047	.001	.002	2	6
STAD	Insulin secretion involved in cellular response to glucose stimulus →	+0.059	+0.025	<.001	.004	3	5
LUSC	Autophagy of mitochondrion →	+0.041	+0.034	<.001	.005	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,095 associations by consensus.

Intracellular glucose homeostasis by H2AL1QP expression — STAD

Explore this box plot interactively →