H2AL1QP

Across TCGA pan-cancer cohorts, H2AL1QP RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of H2AL1QP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where H2AL1QP RNA is repressed in tumor relative to normal tissue. In most cancer types H2AL1QP is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and UCEC are the cancer types where H2AL1QP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2AL1QP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.064	.001	5	view →
LUAD	Female	All	−0.149	.002	4	view →
UCEC	All	All	+0.214	.024	2	view →
KICH	All	All	−0.120	.006	2	view →
PRAD	All	All	+0.089	.030	2	view →
LUSC	All	All	−0.055	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

H2AL1QP–KIRC

Open the KIRC breakdown →