H2AL1QP

Across TCGA pan-cancer cohorts, H2AL1QP RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated H2AL1QP data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher H2AL1QP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated H2AL1QP expression acts as an unfavorable survival marker.

SKCM, UVM, and ESCA are the cancer types where H2AL1QP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	II,III,IV	0.157	0.694	<.001	87	view →
UVM	OS	Tertile	III,IV	0.136	0.874	<.001	54	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
OV	OS	Tertile	II,III,IV	0.637	0.705	.011	30	view →
LIHC	DFS	Tertile	All	0.080	0.553	.004	27	view →
BRCA	DFS	Tertile	All	0.421	0.542	.023	12	view →
LGG	DFS	Quartile	All	0.625	0.785	.020	11	view →
READ	DFS	Tertile	IV	0.255	0.628	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

H2AL1QP–SKCM (DFS)

Open the SKCM breakdown →