H2AJ

Across TCGA cell cohorts, H2AJ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,487 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible H2AJ-associated GO terms across cancer lineages are Mitochondrial RNA metabolic process, Regulation of viral entry into host cell, and Positive regulation of alpha-beta T cell proliferation. Each is linked with H2AJ in more than 6 cancer types. Because this analysis shows association rather than direction, both H2AJ-to-partner and partner-to-H2AJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA metabolic process grouped by H2AJ-low versus H2AJ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AJ→partner) and Y-score (partner→H2AJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial RNA metabolic process →	-0.088	-2.709	.001	<.001	3	6
BLOOD_Leukemia	Regulation of viral entry into host cell →	+0.095	+2.336	<.001	<.001	3	6
KIDNEY	Positive regulation of alpha-beta T cell proliferation →	+0.221	+1.694	.002	<.001	3	6
BONE	DNA strand elongation involved in DNA replication →	-0.177	-2.463	.001	.004	3	6
SOFT_TISSUE	Lagging strand elongation →	-0.101	-2.908	.002	<.001	3	6
BONE	Mitochondrial tRNA modification →	-0.110	-2.736	.005	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,487 associations by consensus.

Mitochondrial RNA metabolic process by H2AJ expression — BONE

Explore this box plot interactively →