H2AJ

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, H2AJ mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible H2AJ-associated genes across cancer lineages are FAM205A. Each is linked with H2AJ in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AJ-to-partner and partner-to-H2AJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by H2AJ-low versus H2AJ-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AJ→partner) and Y-score (partner→H2AJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFAM205A →+0.025+4.614<.001.00231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

FAM205A by H2AJ expression — LARGE_INTESTINE

Box plot of FAM205A in H2AJ-low vs H2AJ-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration