H2AC8

Across TCGA patient cohorts, H2AC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,641 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2AC8-associated proteins across cancer lineages are HAT1, MAD2L1, and PRIM2. Each is linked with H2AC8 in more than 5 cancer types. Because this analysis shows association rather than direction, both H2AC8-to-partner and partner-to-H2AC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AC8 versus HAT1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC8→partner) and Y-score (partner→H2AC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HAT1 →	+0.605	+1.341	<.001	<.001	3	6
GBM	MAD2L1 →	+0.546	+0.951	<.001	<.001	3	6
LSCC	PRIM2 →	+0.509	+1.055	<.001	<.001	3	6
LSCC	RBBP7 →	+0.294	+0.916	<.001	<.001	3	5
GBM	ZWILCH →	+0.524	+1.267	.002	<.001	3	5
LUAD	TTK_S436 →	+1.207	+1.151	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,641 associations by consensus.

H2AC8 vs HAT1 — LSCC

Explore this scatter interactively →