Across TCGA patient cohorts, H2AC21 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2AC21-associated genes across cancer lineages are RNU6-1299P, TEX28, and RNMTL1P1. Each is linked with H2AC21 in more than 2 cancer types. Because this analysis shows association rather than direction, both H2AC21-to-partner and partner-to-H2AC21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC21→partner) and Y-score (partner→H2AC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-1299P →	+0.339	+5.201	<.001	.007	3	3
UCEC	TEX28 →	+0.054	+3.386	.008	.008	3	2
BLCA	RNMTL1P1 →	+0.113	+5.289	<.001	.003	3	2
UCEC	PPIAP7 →	+0.256	+4.162	.001	.001	3	1
UCEC	OR4B1 →	+0.147	+5.186	<.001	<.001	3	1
UCEC	GSC2 →	+0.180	+3.715	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

Exploration

H2AC21 survival (RNA) · tumor vs normal (RNA) · all H2AC21 data types