Q-omics provides the consensus-scored PPIAP7 profile across patient tissues and cancer cell-line models. PPIAP7 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, PPIAP7 is differentially expressed in 2, with the highest sampling consensus in UCEC. Additionally, PPIAP7 RNA expression shows 5,115 significant pathway-activity associations, with the highest sampling consensus in UCEC. Together, these results highlight STAD, and UCEC as cancer lineages where PPIAP7 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPIAP7 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPIAP7 survival associations across molecular data types. PPIAP7 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPIAP7 RNA expression–survival associations across cancer types. High PPIAP7 expression shows unfavorable associations in STAD, ACC, MESO, UVM and UCEC, but favorable associations in SKCM. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify STAD as the clearest survival context for PPIAP7 RNA expression.
This table summarizes PPIAP7 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for PPIAP7. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPIAP7 shows higher tumor expression in UCEC and LIHC. The UCEC box plot shows higher PPIAP7 RNA expression in tumor versus normal tissue (log2 FC = +0.285, t-test p = .035).
This table shows molecular features associated with PPIAP7 in patient tissues and cancer cell lines. In patient samples, PPIAP7 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
