Across TCGA pan-cancer cohorts, PPIAP7 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PPIAP7’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where PPIAP7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAP7 is over-expressed in tumor.
UCEC and LIHC are the cancer types where PPIAP7 tumor–normal differential expression is most reproducible.