H2AC19

Across TCGA patient cohorts, H2AC19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,265 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible H2AC19-associated GO terms across cancer lineages are Innate immune response in mucosa, Organ or tissue specific immune response, and Protein localization to CENP-A containing chromatin. Each is linked with H2AC19 in more than 15 cancer types. Because this analysis shows association rather than direction, both H2AC19-to-partner and partner-to-H2AC19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Innate immune response in mucosa grouped by H2AC19-low versus H2AC19-high in OV.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC19→partner) and Y-score (partner→H2AC19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	Innate immune response in mucosa →	+0.089	+0.692	<.001	<.001	3	16
LAML	Organ or tissue specific immune response →	+0.071	+0.440	<.001	<.001	2	16
COAD	Protein localization to CENP-A containing chromatin →	+0.067	+0.026	<.001	.005	1	15
ESCA	Negative regulation of megakaryocyte differentiation →	+0.048	+0.619	<.001	<.001	3	9
PAAD	GTP biosynthetic process →	+0.033	+0.045	<.001	<.001	3	7
LAML	Antimicrobial humoral immune response mediated by antimicrobial peptide →	+0.048	+0.301	.006	.007	1	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,265 associations by consensus.

Innate immune response in mucosa by H2AC19 expression — OV

Explore this box plot interactively →