H2AC19

Across TCGA pan-cancer cohorts, H2AC19 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of H2AC19’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where H2AC19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2AC19 is over-expressed in tumor.

STAD, BRCA, and LUAD are the cancer types where H2AC19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2AC19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.283	.014	4	view →
BRCA	Female	All	+0.117	.001	4	view →
LUAD	Male	All	+0.078	.018	4	view →
LUSC	Male	II,III,IV	+0.054	.003	4	view →
KIRC	Female	III,IV	+0.059	.014	3	view →
PRAD	All	All	+0.100	.009	2	view →
HNSC	All	IV	+0.070	.029	2	view →
LIHC	All	All	+0.045	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

H2AC19–STAD

Open the STAD breakdown →