Across TCGA patient cohorts, H2AC18 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,903 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible H2AC18-associated proteins across cancer lineages are MKI67, ATAD2_S342, and TOP2A. Each is linked with H2AC18 in more than 6 cancer types. Because this analysis shows association rather than direction, both H2AC18-to-partner and partner-to-H2AC18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC18→partner) and Y-score (partner→H2AC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MKI67 →	+0.674	+0.848	<.001	<.001	3	7
OV	ATAD2_S342 →	+1.504	+1.231	<.001	<.001	3	7
LSCC	TOP2A →	+0.954	+0.612	<.001	.001	3	6
UCEC	UBE2S →	+0.530	+1.164	<.001	<.001	3	6
LUAD	MKI67_S357 →	+1.666	+0.683	<.001	<.001	3	6
UCEC	NCAPG →	+0.509	+0.903	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,903 associations by consensus.

Exploration

H2AC18 survival (RNA) · tumor vs normal (RNA) · all H2AC18 data types