H2AC12

Across TCGA patient cohorts, H2AC12 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,610 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible H2AC12-associated proteins across cancer lineages are CHTF18_S871, MCM2_S41, and MCM2. Each is linked with H2AC12 in more than 8 cancer types. Because this analysis shows association rather than direction, both H2AC12-to-partner and partner-to-H2AC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AC12 versus CHTF18_S871 in LUAD, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC12→partner) and Y-score (partner→H2AC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CHTF18_S871 →	+0.790	+1.142	<.001	<.001	3	9
LUAD	MCM2_S41 →	+0.847	+1.035	<.001	<.001	3	9
LUAD	MCM2 →	+0.853	+1.152	<.001	<.001	3	8
LUAD	MCM3 →	+0.882	+1.197	<.001	<.001	3	8
LUAD	MCM6 →	+0.903	+1.203	<.001	<.001	3	8
GBM	RRM1 →	+0.662	+1.612	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,610 associations by consensus.

H2AC12 vs CHTF18_S871 — LUAD

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