H2AC12

Across TCGA patient cohorts, H2AC12 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible H2AC12-associated genes across cancer lineages are Fibroblasts and CD4+ Tcm. Each is linked with H2AC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC12-to-partner and partner-to-H2AC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by H2AC12-low versus H2AC12-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC12→partner) and Y-score (partner→H2AC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Fibroblasts →	+0.022	+5.797	<.001	.035	3	1
ESCA	CD4+ Tcm →	+0.010	+4.068	.018	.015	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Fibroblasts by H2AC12 expression — SKCM

Explore this box plot interactively →