Across TCGA patient cohorts, H2AC11 mutation is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2AC11-associated genes across cancer lineages are MIR6893, RNU6-1216P, and RN7SKP224. Each is linked with H2AC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC11-to-partner and partner-to-H2AC11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC11→partner) and Y-score (partner→H2AC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6893 →	+0.366	+2.370	.005	.008	3	2
BLCA	RNU6-1216P →	+0.374	+3.095	<.001	.005	3	2
BLCA	RN7SKP224 →	+0.048	+4.229	<.001	.006	3	2
LIHC	LINC01047 →	+0.040	+5.758	<.001	.003	3	2
LUAD	MIR541 →	+0.336	+4.631	.001	.008	3	2
COAD	NANOGNB →	+0.066	+5.357	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

Exploration

H2AC11 survival (RNA) · tumor vs normal (RNA) · all H2AC11 data types