Across TCGA patient cohorts, H2AC11 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2AC11-associated genes across cancer lineages are P-Cadherin, YB-1, and Caspase-7-cleavedD198. Each is linked with H2AC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC11-to-partner and partner-to-H2AC11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC11→partner) and Y-score (partner→H2AC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	P-Cadherin →	-0.175	-2.990	.027	.036	3	1
UCEC	YB-1 →	+0.212	+3.196	.015	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.719	+3.169	.027	.020	3	1
UCEC	ATM →	-0.836	-3.169	<.001	.020	2	1
UCEC	Myosin-IIa →	+0.265	+3.177	.009	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

H2AC11 survival (RNA) · tumor vs normal (RNA) · all H2AC11 data types