H2AB3

Across TCGA patient cohorts, H2AB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 1,815 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible H2AB3-associated proteins across cancer lineages are VAMP5, PKN2, and TRIM28_S258. Each is linked with H2AB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both H2AB3-to-partner and partner-to-H2AB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AB3 versus VAMP5 in LUAD, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AB3→partner) and Y-score (partner→H2AB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	VAMP5 →	+0.515	+0.040	<.001	<.001	3	2
LUAD	PKN2 →	-0.254	-0.052	.003	.003	3	2
BRCA	TRIM28_S258 →	+0.602	+0.200	.002	.001	3	2
BRCA	GSTM3_S122 →	-0.719	-0.155	.005	<.001	3	2
GBM	DBH →	+0.668	+0.051	.006	.004	3	2
LUAD	EPS8L1_T187 →	-0.586	-0.037	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,815 associations by consensus.

H2AB3 vs VAMP5 — LUAD

Explore this scatter interactively →