H2AB3

Across TCGA pan-cancer cohorts, H2AB3 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of H2AB3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where H2AB3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2AB3 is over-expressed in tumor.

HNSC are the cancer types where H2AB3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2AB3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.011	.041	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

H2AB3–HNSC

Open the HNSC breakdown →