H2AB1

Across TCGA patient cohorts, H2AB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,315 significant associations in total. UVM shows the largest number of these associations.

The most reproducible H2AB1-associated GO terms across cancer lineages are Regulation of protein localization to plasma membrane, Regulation of protein localization to cell periphery, and Regulation of protein localization to membrane. Each is linked with H2AB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both H2AB1-to-partner and partner-to-H2AB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to plasma membrane grouped by H2AB1-low versus H2AB1-high in MESO.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AB1→partner) and Y-score (partner→H2AB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	Regulation of protein localization to plasma membrane →	+0.031	+0.160	<.001	<.001	3	4
UVM	Regulation of protein localization to cell periphery →	+0.029	+0.076	<.001	<.001	3	4
UCS	Regulation of protein localization to membrane →	+0.027	+0.224	<.001	.003	3	4
UVM	Aerobic respiration →	+0.035	+0.053	.001	.001	2	4
UVM	Nucleoside phosphate biosynthetic process →	+0.026	+0.052	<.001	.002	3	3
UVM	Cellular response to light stimulus →	+0.032	+0.051	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,315 associations by consensus.

Regulation of protein localization to plasma membrane by H2AB1 expression — MESO

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