H2AB1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, H2AB1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of H2AB1’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where H2AB1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2AB1 is over-expressed in tumor.

ESCA and LIHC are the cancer types where H2AB1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2AB1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
ESCAFemaleAll+0.116.0212view →
LIHCAllAll+0.045.0151view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

H2AB1–ESCA

Tumor-vs-normal expression box plot for H2AB1 RNA in ESCA.

Open the ESCA breakdown →

Exploration