H2AB1

Across TCGA cell cohorts, H2AB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,163 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H2AB1-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Negative regulation of tumor necrosis factor-mediated signaling pathway, and Negative regulation of hemopoiesis. Each is linked with H2AB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both H2AB1-to-partner and partner-to-H2AB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tumor necrosis factor-mediated signaling pathway grouped by H2AB1-low versus H2AB1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AB1→partner) and Y-score (partner→H2AB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.042	+1.083	.007	.007	3	3
BLOOD_Lymphoma	Negative regulation of tumor necrosis factor-mediated signaling pathway →	+0.073	+1.698	<.001	.004	3	3
BLOOD_Lymphoma	Negative regulation of hemopoiesis →	+0.054	+1.129	<.001	.005	3	3
BLOOD_Lymphoma	Lens development in camera-type eye →	+0.092	+1.721	<.001	<.001	3	3
BLOOD_Lymphoma	Lens morphogenesis in camera-type eye →	+0.089	+2.258	<.001	<.001	3	3
BLOOD_Lymphoma	Late endosome to vacuole transport via multivesicular body sorting pathway →	+0.032	+1.437	.009	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,163 associations by consensus.

Regulation of tumor necrosis factor-mediated signaling pathway by H2AB1 expression — BLOOD_Lymphoma

Explore this box plot interactively →