H1-3

Across TCGA patient cohorts, H1-3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,121 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H1-3-associated proteins across cancer lineages are PRKAR2A, CDK1, and CHTF18_S871. Each is linked with H1-3 in more than 5 cancer types. Because this analysis shows association rather than direction, both H1-3-to-partner and partner-to-H1-3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H1-3 versus PRKAR2A in HNSC, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-3→partner) and Y-score (partner→H1-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRKAR2A →	-0.262	-1.281	<.001	<.001	3	6
GBM	CDK1 →	+0.677	+1.150	<.001	<.001	3	6
LSCC	CHTF18_S871 →	+0.828	+0.800	<.001	.001	3	6
LUAD	HNRNPK_S216 →	+1.339	+1.172	<.001	<.001	3	6
UCEC	MAD2L1 →	+0.567	+1.716	<.001	<.001	3	6
LUAD	MCM2_S27 →	+0.667	+0.877	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,121 associations by consensus.

H1-3 vs PRKAR2A — HNSC

Explore this scatter interactively →