Across TCGA patient cohorts, GZMM RNA expression is significantly associated with the protein abundance of many other proteins, with 16,544 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GZMM-associated proteins across cancer lineages are IL16, ANKRD44, and LCP1. Each is linked with GZMM in more than 9 cancer types. Because this analysis shows association rather than direction, both GZMM-to-partner and partner-to-GZMM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMM→partner) and Y-score (partner→GZMM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IL16 →	+0.716	+0.927	<.001	<.001	3	10
LSCC	ANKRD44 →	+0.518	+0.984	<.001	<.001	3	10
GBM	LCP1 →	+0.687	+0.319	<.001	<.001	3	10
LSCC	LCP2 →	+0.526	+0.935	<.001	<.001	3	10
UCEC	LPXN →	+0.607	+1.242	<.001	<.001	3	10
UCEC	LSP1 →	+0.664	+1.117	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,544 associations by consensus.

Exploration

GZMM survival (RNA) · tumor vs normal (RNA) · all GZMM data types