Across TCGA patient cohorts, GUCY2EP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,895 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GUCY2EP-associated GO terms across cancer lineages are Aminoglycoside antibiotic metabolic process, Quinone metabolic process, and Response to nitrosative stress. Each is linked with GUCY2EP in more than 12 cancer types. Because this analysis shows association rather than direction, both GUCY2EP-to-partner and partner-to-GUCY2EP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY2EP→partner) and Y-score (partner→GUCY2EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Aminoglycoside antibiotic metabolic process →	+0.139	+0.872	<.001	<.001	3	13
STAD	Quinone metabolic process →	+0.041	+0.107	<.001	<.001	3	12
LUSC	Response to nitrosative stress →	+0.047	+0.342	<.001	<.001	3	11
LUSC	Polyketide metabolic process →	+0.144	+0.925	<.001	<.001	3	11
KIRP	Primary alcohol catabolic process →	+0.070	+0.485	<.001	<.001	3	11
STAD	Response to toxic substance →	+0.035	+0.101	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,895 associations by consensus.

Exploration

GUCY2EP survival (RNA) · tumor vs normal (RNA) · all GUCY2EP data types