GUCA2A

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GUCA2A RNA expression is significantly associated with the mutation status of many other genes, with 1,106 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GUCA2A-associated genes across cancer lineages are HK3, KNG1, and ATG2B. Each is linked with GUCA2A in more than 2 cancer types. Because this analysis shows association rather than direction, both GUCA2A-to-partner and partner-to-GUCA2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA2A→partner) and Y-score (partner→GUCA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaHK3 →+3.969+0.026.009<.00133
BLOOD_LeukemiaKNG1 →+4.384+0.031.006<.00132
OESOPHAGUSATG2B →+3.584+0.486.008.00832
LIVERHSPG2 →+3.502+0.973.007.00232
KIDNEYKIF13B →+5.000+0.043.005<.00132
UPPER_AERODIGESTIVE_TRACTPLCH2 →+4.736+0.065.009<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,106 associations by consensus.

Exploration