GTSE1-DT

Across TCGA pan-cancer cohorts, GTSE1-DT RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated GTSE1-DT data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GTSE1-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GTSE1-DT expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and LIHC are the cancer types where GTSE1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.868	0.725	.001	76	view →
HNSC	DFS	Tertile	IV	0.718	0.498	<.001	47	view →
LIHC	OS	Quartile	II,III,IV	0.283	0.584	.001	43	view →
PAAD	OS	Median	All	0.534	0.249	<.001	41	view →
UVM	OS	Median	All	0.784	0.384	.001	39	view →
ACC	DFS	Quartile	All	0.161	0.665	<.001	32	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.599	.004	31	view →
ESCA	DFS	Median	All	1.000	0.481	.003	30	view →
READ	DFS	Median	All	0.657	0.283	.010	24	view →
LUSC	OS	Median	All	0.830	0.687	<.001	23	view →
CESC	OS	Tertile	II,III,IV	0.893	0.670	.004	22	view →
SKCM	DFS	Median	IV	0.732	0.067	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

GTSE1-DT–UCEC (DFS)

Open the UCEC breakdown →