GTPBP8

Across TCGA patient cohorts, GTPBP8 mutation is significantly associated with the RNA expression of many other genes, with 803 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP8-associated genes across cancer lineages are RN7SL354P, CDRT15P8, and FAM96AP1. Each is linked with GTPBP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTPBP8-to-partner and partner-to-GTPBP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL354P grouped by GTPBP8-low versus GTPBP8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP8→partner) and Y-score (partner→GTPBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL354P →	+0.241	+2.374	.001	.006	3	2
READ	CDRT15P8 →	+0.092	+4.421	<.001	.009	3	1
CESC	FAM96AP1 →	+0.119	+7.584	<.001	<.001	3	1
CESC	LINC02559 →	+1.780	+6.342	<.001	.001	3	1
CESC	RNU6-362P →	+0.921	+7.584	<.001	<.001	3	1
CESC	FAM8A2P →	+0.056	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 803 associations by consensus.

RN7SL354P by GTPBP8 expression — UCEC

Explore this box plot interactively →