GTPBP3

Across TCGA patient cohorts, GTPBP3 mutation is significantly associated with the RNA expression of many other genes, with 1,015 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP3-associated genes across cancer lineages are UTP15, PLRG1, and PRIM1. Each is linked with GTPBP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTPBP3-to-partner and partner-to-GTPBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTP15 grouped by GTPBP3-low versus GTPBP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP3→partner) and Y-score (partner→GTPBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UTP15 →	+0.431	+3.354	.003	.005	3	3
UCEC	PLRG1 →	+0.440	+3.191	.006	.009	3	3
UCEC	PRIM1 →	+0.677	+2.354	.003	.003	3	3
UCEC	RNU6-751P →	+0.110	+3.736	<.001	.009	3	3
BRCA	RN7SL248P →	+0.103	+5.786	<.001	.001	3	2
UCEC	TUBGCP5 →	+0.495	+2.354	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,015 associations by consensus.

UTP15 by GTPBP3 expression — UCEC

Explore this box plot interactively →